Ganondagan (pronounced ga-NON-da-gan) preserves the site of a major 17th-century Seneca town that was home to an estimated 4,500 people before it was destroyed by a French military expedition in 1687. Located on a hilltop near Victor, southeast of Canandaigua Lake, the site is the only New York State Historic Site dedicated to a Native American community. The Seneca Art & Culture Center, opened in 2015, is the centerpiece—a modern interpretive facility with permanent exhibits on Haudenosaunee (Iroquois) history, culture, and contemporary life.

The grounds include a full-size reconstructed Seneca bark longhouse, walking trails through the former town site, and an ethnobotanical trail identifying plants used by the Seneca for food, medicine, and construction. Events throughout the year include the Dance & Music Festival in July, which brings Haudenosaunee performers and artisans from across the region. Ganondagan offers a perspective on Finger Lakes history that predates European settlement by centuries and provides essential context for understanding the land that the wine trails, parks, and towns now occupy.